The men's draw at the US Open looks wide open after Sinner's withdrawal, leaving Zverev as the top seed. Alcaraz, the defending champion, returns after a long injury layoff and will face Safiullin first. Djokovic, on the other hand, starts against Navone, with formidable opponents on the horizon. The two stars could meet in the semifinals, while other players look to take advantage of this unprecedented situation. The tournament begins on August 30.